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Spread of Gamma (P.1) Sub-Lineages Carrying Spike Mutations Close to the Furin Cleavage Site and Deletions in the N-Terminal Domain Drives Ongoing Transmission of SARS-CoV-2 in Amazonas, Brazil

Felipe Gomes Naveca,Valdinete Nascimento,Victor Souza,André de Lima Corado,Fernanda Nascimento,George Silva,Matilde Contreras Mejía,Maria Júlia Brandão,Ágatha Costa,Débora Duarte,Karina Pessoa,Michele Jesus,Luciana Gonçalves,Cristiano Fernandes,Tirza Mattos,Ligia Abdalla,João Hugo Santos,Alex Martins,Fabiola Mendonça Chui,Fernando Fonseca Val,Gisely Cardoso de Melo,Mariana Simão Xavier,Vanderson de Souza Sampaio,Maria Paula Mourão,Marcus Vinícius Lacerda,Érika Lopes Rocha Batista,Alessandro Leonardo Álvares Magalhães,Nathânia Dábilla,Lucas Carlos Gomes Pereira,Fernando Vinhal,Fabio Miyajima,Fernando Braga Stehling Dias,Eduardo Ruback dos Santos,Danilo Coêlho,Matheus Ferraz,Roberto Lins,Gabriel Luz Wallau,Edson Delatorre,Tiago Gräf,Marilda Mendonça Siqueira,Paola Cristina Resende,Gonzalo Bello

Microbiology Spectrum（2022）

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Abstract
The continuous evolution of SARS-CoV-2 is an expected phenomenon that will continue to happen due to the high number of cases worldwide. The present study analyzed how a Variant of Concern (VOC) could still circulate in a population hardly affected by two COVID-19 waves and with vaccination in progress.
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