Efficacy of total flavonoids of Rhizoma drynariae on the blood vessels and the bone graft in the induced membrane

Shuyuan Li,Yue Li,Zexin Jiang,Cheng Hu,Ya Gao,Qishi Zhou

Phytomedicine（2022）

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摘要

•TFRD could promote the vascularization and the expression of angiogenesis- related factors in the induced membrane.•TFRD should accelerate the mineralization of bone graft throngh activating the BMP-Smad pathway.•The main ingredients of TFRD are naringin and neoeriocitrin.•This study provides a new method for perfecting the IMT.

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关键词

Total flavonoids of Rhizoma drynariae,Induced membrane,Vessel,Bone defect,BMP-SMAD pathway

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