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Puckering the Planar Landscape of Fragments: Design and Synthesis of a 3D Cyclobutane Fragment Library

David J. Hamilton, Marieke Beemsterboer, Caroline M. Carter, Jasmina Elsayed, Rilana E. M. Huiberts,Hanna F. Klein,Peter O'Brien,Iwan J. P. de Esch,Maikel Wijtmans

CHEMMEDCHEM（2022）

Cited 7|Views43
Key words
Fragment-based drug discovery (FBDD),Drug design,Library design,Cyclobutane,Three-dimensional (3D)
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