[Effect of moxibustion on M2 and P2X3 receptors of bladder tissue in rats with neurogenic bladder of detrusor areflexia after lumbar-sacral spinal cord injury].
Zhongguo zhen jiu = Chinese acupuncture & moxibustion（2022）
Abstract
Moxibustion at "Guanyuan" (CV 4) and "Shenque" (CV 8) may effectively improve bladder function in the rats with NB of detrusor areflexia after lumbar-sacral spinal cord injury and its underlying mechanism is related to promoting the release of Ach and up-regulating the expression of M2 receptor, thereby enhancing the release of ATP and increasing the expression of P2X3 receptor. Eventually, detrusor contraction is improved.
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Key words
M2 receptor,P2X3 receptor,detrusor areflexia,lumbar-sacral spinal cord injury,moxibustion,neurogenic bladder
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