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Aspirin, heparin and ischemia time in microvascular free flap surgery - their influence and an optimal anticoagulation protocol

René Rothweiler,Vanessa Gerlach,Pit Voss,Philipp Poxleitner,Michael Ermer,Christian Gross,Christian Schwer,Kirstin Vach,Johannes Kalbhenn,Marc Metzger

Journal of Stomatology, Oral and Maxillofacial Surgery（2022）

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Abstract
Anticoagulation regimes in microvascular surgery can influence the postoperative complication rate. The optimal protocol should consist of a combination of ASA and UFH for the intraoperative and direct postoperative phase. Prolonged administration of ASA as well as doses >500 IU/ h of UFH are to be avoided due to the increased complication rate.
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Key words
Microvascular surgery,Acetylsalicylic acid,Unfractionated heparin,Flap loss,Anticoagulation protocols
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