In memory of Professor Iain Wilkinson: cognitive and neuroimaging endophenotypes in a consanguineous schizophrenia multiplex family.

Iain D Wilkinson,Tariq Mahmood, Sophia Faye Yasmin,Anneka Tomlinson,Jamshid Nazari,Hamid Alhaj, Soumaya Nasser El Din,Joanna Neill, Chhaya Pandit, Shahzad Ashraf,Alastair G Cardno,Steven J Clapcote,Chris F Inglehearn,Peter W Woodruff

Psychological medicine（2022）

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摘要

In this family, homozygosity at the 13q risk locus was associated with impaired cognition, white matter integrity, and altered laterality of neural activation.

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关键词

Cognition,connectivity,consanguinity,endophenotypes,fractional anisotropy,schizophrenia

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