P70 Calibrating Cardiovascular Disease Policy Model Using Large Cohort Data

R Wu,C Williams,I Schlackow,J Zhou,J Emberson,C Reith,A Keech,J Robson,K Wilkinson,J Armitage,R Collins,A Gray,J Simes,C Baigent,B Mihaylova

Value in Health（2022）

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Abstract

Declining cardiovascular disease (CVD) morbidity and mortality over the last decades suggest that policy models developed using historic data likely overestimate current risks. We illustrate an approach to calibrating a micro-simulation CVD model, developed using historic clinical trials data, using the 2006-2020 UK Biobank cohort.

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Key words

large cohort data,cardiovascular disease,policy

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