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Synthesis and α-D-Glucosidase Inhibitory Activity of N-Substituted Valiolamine Derivatives as Potential Oral Antidiabetic Agents.

Satoshi Horii,Hiroshi Fukase,T. Matsuo,Yukihiko Kameda,Naoki Asano,Katsuhiko Matsui

ChemInform（1986）

Cited 288|Views0
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Abstract
Ausgehend vom Valiolamin (I) bzw. Valienamin (IV) wird durch reduktive Alkylierung, Ringöffnung von Oxiranen wie (IX) sowie durch N‐Alkylierung eine Reihe von N‐substituierten Derivaten dieser Amine hergestellt.
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Key words
potential oral antidiabetic agents,d-glucosidase,n-substituted
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