Practical Acid-Catalyzed Acylation of Sulfonamides with Carboxylic Acid Anhydrides.

Michael Tolar Martin,Frank Roschangar,John F. Eaddy

ChemInform（2003）

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摘要

A highly efficient reaction between sterically and electronically diverse sulfonamides and carboxylic acid anhydrides to furnish monoacylated N-acylsulfonamides is described. This represents the first systematic disclosure of the scope of sulfuric acid-catalyzed acylation of sulfonamides.

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