Discovery of Novel Hydroxy Pyrazole Based Factor IXa Inhibitor.

Dange Vijaykumar,Paul A. Sprengeler,Michael B. Shaghafi,Jeffrey R. Spencer, Brad A. Katz,Christine Yu,Roopa Rai,Wendy B. Young,Brian E. Schultz,James W. Janc

ChemInform（2006）

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摘要

Synthesis and biological data of a novel selective and efficacious factor IXa inhibitor are described along with its crystal structure in factor VIIa.

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inhibitor

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