Influence of Breast Milk Jaundice on Renal Function and Its Early Interference Treatment

Objective To investigate the renal function changes of the children with breast milk jaundice(BMJ) and effect of early interference treatment on renal function. Methods Serum bilirubin and urine - minim protein (β2-MG,α1-MG, Alb and IgG) of the 50 patients with BMJ were measured when they were in hospital within 12 hours and the last day separately , at the same time, 20 healthy newborns had been chosen to serve as control group. Results Compared with control group, the urine minim protein of treatment group increased with the rise of serum bilirubin. When serum bilirubin was 205.2 - 256.5 μmol/L, urine β2- MG had mild increasing (P0.05), when it was 256.6 - 342.0 μmol/L,β2 - MG and α1 - MG increased markedly(all P0.01),and Alb had been increasing (P0.05). Nevertheless,urine β2-MG,α1-MG and Alb almost returned to normal before they left hospital. Conclusion BMJ may damage renal function temporarily, but renal function recovered faster after early interference treatment.