Content Determination of Serum Nifedipine by Micell Liquid Chromatography

China Pharmacy(2005)

引用 0|浏览0
暂无评分
摘要
OBJECTIVE:To establish micell liquid chromatography for the content determination of nifedipine in human serum.METHODS:The determination was performed on C 18 chromatographic column,the mobile phase consisted of methanol-water(60∶40,which containing20mmol/L SDS),the detection wavelength was248nm,the sensitivity was0.01AUFS,the flow rate was1.0ml/min and the chart speed was2.1mm/min.RESULTS:The linear range for nifedipine was4~40ng/ml(r=1.0002),the average recovery was98.15%(RSD=1.49%).CONCLUSION:The method is simple,accuˉrate,feasible,reproducible,and it can be used as a new method for the monitoring of clinic haemoconcentration of nifedipine.
更多
查看译文
关键词
serum nifedipine,micell liquid chromatography
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要