Highly Efficient Synthesis of Aldenamines from Carboxamides by Iridium‐Catalyzed Silane—Reduction/Dehydration under Mild Conditions.

The combination of IrCl(CO)(PPh3)2 with 1,1,3,3-tetramethyldisiloxane or poly(methylhydrosiloxane) (PMHS) is found to be an efficient catalyst system for the preparation of aldenamines from carboxamides; in particular, facile removal of silicone and iridium residues from the product can be achieved by the use of PMHS.