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Inhibitive effect of ceftriaxone to Staphylococcus epidermidis biofilm

Zhu Dong

Labmedicine（2007）

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Abstract
Objective To observe whether ceftriaxone has inhibitive effect on the Staphylococcus epidermidis biofilm,and study the function of antibiotics in the prevention and treatment of Staphylococcus infection. Methods15 Staphylococcus epidermidis whose biofilm were positive were screened by adhesive test. The inhibitive effect of the drugs with different concentration were observed. Results Ceftriaxone could inhibit the Staphylococcus epidermidis biofilm formation while ceftazidime,erythromycin could not.Vancomycin could kill Staphylococcus strongly,but could not inhibit The biofilm formation. ConclusionsCeftriaxone is useful to prevent Staphylococcus epidermidis infection by inhibiting adhesive effect.
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Key words
ceftriaxone,biofilm,inhibitive effect
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