The significance of surgery combined with interventional therapy in primary hepatic carcinoma

Objective:To explore the value of surgery combined with interventional therapy in primary hepatic carcinoma.Methods:There were 69 cases of primary hepatic carcinoma.Surgical operation was done,and then TAI or TACE was carried out in 41 cases(group 1).TACE was carried out first,and then surgical operation was done between 7 days and 1 month,TAI or TACE was carried out again 1 to 6 months in 28 cases(group 2).All cases received 236 times of TAI or TACE(the most 11 times,lest 1 time,average 3.4 times).Surgical operation and interventional therapy was successful done and with no complications.Remnant cancer was found in 9 cases with angiography 1～2 months later(9/41),and in 18 cases recurrence cancer was found after 2 years in group 1.No remnant cancer was found,and recurrence cancer was found in 7 patients after 2 years in group 2.AFP level was in normal range or nearly normal range after surgical operation.Survival rate was 100% in half year,89.3% in 1 year,68.0% in 2 years, 57.3% in 3 years and 43.8% in 5 years.Conclusion:Pre-operational TACE could make more opportunity to radical surgery,and it also could prevent recurrence of the tumor.The combination of surgery and TACE is an important way in improvement therapy effect and survival rate of the patient.