Analysis on chromosome karyotypes in 80 cases of abnormal fertility

Objective:To explore the relationship between abnormal karyotypes and abnormal fertility.Methods:2 485 genetic counseling patients in the Institute for Reproductive Medicine of Jilin province were investigated from May 2004 to May 2008,whose peripheral blood lymphocytes were cultured and the abnormal karyotypes were analyzed.Results:257 cases(10.34%) of abnormal karyotypes were found in 2 485 patients,including 154 cases(59.92%) of sex chromosome abnormalities and 103 cases(40.08%) of euchromosome abnormalities.Conclusion:Abnormal karyotype is closely related to abnormal fertility,karyotype analysis is conducive to clinical diagnosis,also provides the basis for genetic counseling.