Diastereo- and Enantioselective Synthesis of α,β-Epoxyketones Using Aqueous NaOCl in Conjunction with Dihydrocinchonidine Derived Phase-Transfer Catalysis at Room Temperature. Scope and Limitations.

In this paper we present studies into the scope and limitations of asymmetric PTC epoxidation of enones and the oxidation–epoxidation of allylic alcohols using aqueous NaOCl in conjunction with a dihydrocinchonidine derived quaternary ammoniumsaltcatalyst.