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Cyclic AMP acts through Rap1 and JNK signaling to increase expression of cutaneous smooth muscle α2C-adrenoceptors

Ali H. Eid,Maqsood A. Chotani,Srabani Mitra, T. J. Miller,Nicholas A. Flavahan

American Journal of Physiology-heart and Circulatory Physiology（2008）

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Abstract
Cold increases cutaneous vasoconstriction by unmasking the contractile activity of α2C-adrenoceptors (α2C-ARs) in vascular smooth muscle cells (VSMCs), which is mediated by the cold-induced mobiliz...
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cyclic amp,muscle,jnk,rap1
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