Diagnosis and treatment of proteinuria after renal transplantation

Objective To investigate the efficacy of the clinical treatment and the situation of proteinuria after renal transplantation.Methods 131 patients with proteinuria after kidney grafting were needled biopsy.According to the causes of proteinuria after kidney biopsy,they were treated with glucocorticoid,adjustment of immunosuppressive regimens and improvement of microcirculation.Efficacy of the clinical treatment was then evaluated.Results After treatment,the contents of urinary protein,serum creatinine,rate of creatinine clearance,and the blood urea nitrogen were significantly different(P0.05).There were also significant different between the total efficacy and invalid of rejection,nephritis and ischemic-reperfusion injury after treatment(P0.05).Conclusion According to the causes of proteinuria after kidney biopsy,patients may be treated with glucocorticoid,by adjustment of immunosuppressive regimens or improvement of microcirculation.