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Expression of Gelatinases and their Relationship with TGF-β1 and TGF-β1R I in Colon Cancer

Hou De-fa,Zou Qiang,Hao Da-hai

Applied Journal of General Practice（2010）

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Abstract
目的 研究明胶酶(MMP-2,9)与转化生长因子(TGF-β1)及其Ⅰ型受体(TGF-β1R Ⅰ)在大肠癌组织中的蛋白表达及其相互关系.方法 应用免疫组织化学S-P法检测89例大肠癌组织中MMP-2、MMP-9与TGF-β1、TGF-β1R Ⅰ蛋白的表达.结果 大肠癌MMP-2、MMP-9、TGF-β1和TGF-β1R Ⅰ阳性率分别为67.4%、65.2%、85.4%和71.9%;MMP-2表达与...
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Key words
gelatinases,cancer
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