Erratum: Dramatic increase in cortical thickness induced by femoral marrow ablation followed by a 3-month treatment with PTH in rats (Journal of Bone and Mineral Research (2010) 25, (1350-1359) DOI: 10.1002/jbmr.25)

In [1], Fig. 1C was inadvertently omitted. Figure 1 is reprinted here in its entirety. The Publisher regrets the error. Femoral marrow ablation followed by treatment with PTH for 3 months (84 days) increases cortical bone thickness: results of radiographic, pQCT, µCT, and histologic analysis. (A) High-resolution radiograms of the left operated and right unoperated femurs from control, sham-operated, and bone marrow–ablated (bmx) rats that were treated 5 days a week with PBS or PTH for a duration of 21 or 84 days. Two groups of rats were treated with PTH for 21 days and then with PBS or alendronate for 63 days. Note that the representative marrow-ablated femur from rats that were treated with PTH for 84 days is more intensely radiopaque than any other femur and is also more intensely radiopaque than its contralateral femur, which is itself more radiopaque than the control femur. X-ray images are representatives of the overall data. (B) µCT analysis of femoral shafts from control and marrow-ablated femurs from rats treated with PBS or PTH for 21 or 84 days. Note the dramatic increase in cortical thickness of the ablated femur from rats treated with PTH for 84 days. (C) Histologic analysis following calcein labeling. The intramedullary bone formed in response to marrow ablation followed by 21 days of treatment with PTH is undergoing calcification, as demonstrated by the regular fluorescent signal from calcein that has been incorporated into mineralizing bone. Note that after 84 days of treatment with PTH, most of the calcein label highlights the endosteal and periosteal bone surfaces.