Comparative study on localization of motor cortex of patients with brain tumors by rs-fMRI and task-based fMRI
Chinese Journal of Magnetic Resonance Imaging(2012)
Abstract
Objective:To evaluate whether rs-fMRI is appropriate and robust for mapping motor cortex in presurgical planning,by comparing the rs-fMRI and task-based fMRI in mapping motor cortex of brain tumors.Materials and Methods:Twelve patients with brain tumors were selected.Their fMRI dataset was analyzed by FMRIB Software Library Multivariate Exploratory Linear Optimized Decomposition into Independent Components(FSL MELODIC ICA) software(www.fmrib.ox.ac.uk/fsl).Results:The experimental results showed that the motor activation mappings from rs-fMRI are quite similar to those the task-based fMRI in the patients with tumors far from motor cortex activation(patient 1,3,7,8,11).However,in each of the patients with tumor around motor cortex(patient 2,4,5,6,9,10,12),the spatial distribution of motor cortex activation from the rs-fMRI does not match the distribution from the task-based fMRI well.Conclusion:Based on our experimental results,we find that the combination of rs-fMRI and task-based fMRI should be treated as a complementary approach to assessing the sensorimotor area in patients with brain tumors,which cannot be performed by rs-fMRI alone.
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Key words
brain tumors,motor cortex,rs-fmri,task-based
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