The Research Progress of MiR-203 and its Regulation Mechanisms

MicroRNAs(miRNA) are 18-25-nucleotide,single-stranded,non-coding RNAs that participate in many pathological and physiological processes of the body.MiR-203 is a miRNA specially expressed in epithelial tissue.Researches show that miR-203 plays an important role in skin development,skin-related diseases,epithelial tumors and other pathological and physiological processes.The interaction between miR-203 and epigenetic mechanisms is also discovered in the researches on some diseases,while the researches on the regulation mechanisms of miR-203 focus on P63,SOCS-3 and related signal pathways.