The effect observation of valsartan in early diabetic nephropathy

Objective To observe the effect of valsartan in early diabetic nephropathy.Methods 128 cases patients with early diabetic nephropathy were given valsartan 80～160mg,one time a day.After treatment 8 weeks,compared with the blood pressure,the amount of the urinary albminuria,empty stomach blood sugar,the saccharified hemoglobin,the triglyceride,the total cholesterol,the endogenous creatinine clearance rate.Results After treatment,the urinary albumin drops obviously(P0.01),while the blood pressure,the empty stomach blood sugar,the saccharified hemoglobin,the triglyceride,the total cholesterol and the endogenous creatinine clearance rate had no obvious change(P0.05).There was no obvious adverse reaction during therapeutic process.Conclusion Valsartan can reduce the amount of urinary albumin,is one of the effective drug of treating early diabetic nephropathy.