A One‐Pot Three‐Component Reaction to Access 1‐Alkyl‐2‐aryl‐5‐nitrobenzimidazoles under Solvent‐Free Conditions.
ChemInform（2010）
摘要
Abstract A novel and expeditious method to access 1-alkyl-2-aryl-5-nitrobenzimidazoles has been developed. Enlisting solvent-free conditions, 2-fluoro-5-nitroaniline, a primary amine, and substituted aldehyde were melted together in one-pot to generate a variety of 1-alkyl-2-aryl-5-nitrobenzimidazoles.
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