Clinical analysis of 17 middle-aged and elderly patients with dermatomyositis associated with malignant tumors

Objective To analyze the clinical factors relating dermatomyositis associated with malignant tumors.Methods 17 cases treated in the past 3 years of DM associated with malignant tumors were included in the retrospective analysis,and their clinical information was compared to that of 45 DM patients without malignant tumors.Results The incidence of DM associated with malignant tumors was 27.4%.There were various types of tumors with the leading types of gastric cancer,ovarian cancer and esophageal cancer.The levels of ESR,CK,LDH and α-HBDH of DM patients with malignant tumors were higher than those of DM patients without malignant tumors,and the positive rate of tumor markers was higher too.Conclusions These factors,age of 40 years over,the higher levels of ESR,CK,LDH,and α-HBDH and the high positive rate of tumor markers,are related to DM associated with malignant tumor.