Comparison of urinary protein level and composition in deficiency types children with proteinuria

Objective:To observe the distribution of four deficiency types of TCM syndrome in Children with proteinuria and investigate the relativity between it and urinary protein amount and Composition.Methods:56 proteinuria Children with Pi qi-deficiency type,qi-yin deficiency type,Gan-Shen yin-deficiency type and Pi-Shen yang-deficiency type respectively were collected and compared the proportion and the levels of 24hys proteinuria,mALB,IgG,β2-MG,α1-MG and TRF in each type.Results:In the four types,Pi-Shen yang-deficiency type is seldom and the most is qi-yin deficiency type.Compared with Gan-Shen yin-deficiency type[(61.9±88.4)mg/L and(2 226.1±3 135.3)mg/L respectively],the levels of IgG and mAlb in qi-yin deficiency type[(257.6±357.8) mg/L and(4 479.7±3 817.3)mg/L respectively] were significantly higher(P0.05),but no difference in β2-MG,α1-MG and TRF.There were no obviously difference between Gan-Shen yin-deficiency type and Pi qi-deficiency type.There was a increasing tendency the the 24hrs proteinuria value of qi-yin deficiency type higher than those of qi-deficiency type and Gan-Shen yin-deficiency type.The value of β2-MG in Gan-Shen yin-deficiency type had similar tendency than other two types.Conclusion:There is certain relativity between deficiency types of TCM syndrome and urinary protein composition in children with proteinuria.