Alteration of Proteasome System in Aging and Aging-Associated Disorders
International Journal of Drug Development and Research(2015)
Abstract
The proteasome system is crucial in protein metabolism involving in physiological and pathological developments, especially in aging and agingrelated disorders. Here we discussed the relationship of proteasome with other metabolic systems such as lysosome and ribosome as well as the alteration of proteasome system under oxidative stress, aging and other pathological conditions
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Key words
proteasome system,aging-associated
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