Clinical significance of urinary Streptococcus pneumoniae antigen detection for the diagnosis of Streptococcus pneumoniae pneumonia in children

Objective To explore the clinical significance of urinary Streptococcus pneumoniae(Sp)antigen detection for the diagnosis of Sp pneumonia.Methods Sputum samples and blood samples,collected from 300pediatric inpatients with lower respiratory tract infections,were detected for pathogenic bacteria by culture and identification,and urine samples,collected at the same time from the same inpatients,were detected for Sp antigen by colloidal gold method.Results Among 300pediatric inpatients,the positive rates of sputum culture,blood culture and urinary Sp antigen test were 10.33%(31/300),15.67%(47/300)and 19.33%(58/300)respectively.The positive rate of urinary Sp antigen test was higher than the other two methods,and the positive rate of blood culture was higher than sputum culture(P0.05).The sensitivity and specificity of the determination of urinary Sp antigen were 82.98%(39/47)and 92.49%(234/253).Conclusion Urinary Sp antigen detection could be used for assisted diagnosis of Sp pneumonia in children.