Clinicopathological Analysis of Primary Jejunoileal Neoplasm

Objective To analyze the clinical characteristics,pathologic types and features of primary jejunoileal neoplasms,in order to provide clinical experiences for further improvement in the diagnosis of this disease.Methods Clinical data of 62 patients with primary jejunoileal neoplasms between January 2003 and November 2012 were analyzed retrospectively.Results The average age of the patients was(55 ± 16) years,and the age of 83.9% patients was over 40 years old.There were 9 benign and 53 malignant tumors in this series with a ratio of 1:5.9.The 53 malignant tumors consisted of 26 malignant gastrointestinal stromal tumors,15 malignant lymphomas,9 adenocarcinomas,1 leiomyosarcoma,1 sarcomatoid carcinoma and 1 follicular dendritic cell sarcoma.Abdominal pain(44/62,71.0%),bowel obstruction(22/62,35.5%),anemia(16/62,25.8%),abdominal distension or discomfort(11/62,17.7%),hemorrhage(10/62,16.1%) and abdominal mass(8/62,12.9%) were the most frequent clinical features of primary jejunoileal tumors.Correct preoperative diagnosis rate of small intestinal neoplasms was only 25.8%(16/62),and 46 patients were diagnosed by laparotomy examination and postoperative pathological study.Conclusions The early diagnosis for primary jejunoileal neoplasms is usually diff icult because most of them have nonspecif ic clinical manifestations with a high rate of preoperative misdiagnosis.Maintaining a high degree of suspicion and recognizing the possibility of primary jejunoileal neoplasms are very important.