The Study of Photofrin-II Absorption in Esophageal Cancer Cell Line

Objective By measuring the photosensitizer photofrin-Ⅱ concentration of esophageal cancer cell line and esophageal epithelial cell line,the study was to investigate the affinity of tumor cells to the photofrin-Ⅱ,in order to provide the basis for targeted principle in photodynamic therapy.Methods High performance liquid chromatography was applied to measure the photofrin-Ⅱ concentration in immortalized human esophageal epithelial cell line SHEE and its malignant transformation cell line SHEEC,investigate the law of their absorption.Results In a certain time range,the absorption of photofrin-Ⅱ in SHEEC was more than SHEE.Conclusion The absorption of photofrin-Ⅱin SHEEC is more than SHEE.