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Intensive Supportive Care Alone Does Not Impact Survival in a Lethal Non-Human Primate Model of Ebola Virus Disease

Guillaume Poliquin,Duane Funk,Shane Jones,Kaylie Tran,Charlene Ranadheera,Mable Hagan,Kevin Tierney,Allen Grolla,Amrinder Dhaliwal,Alexander Bello,Anders Leung,Cory Nakamura,Darwyn Kobasa,Darryl Falzarano,Hugues Fausther Bovendo,Heinz Feldmann,Murray Kesselman,Gregory Hansen,Jason Gren,George Risi,Mia Biondi,Todd Mortimer,Trina Racine,Yvon Deschambault,Sam Aminian,Jocelyn Edmonds,Ray Saurette,Mark Allan,Lauren Rondeau,Sharron Hadder,Christy Press,Christine DeGraff,Stephanie Kucas,Bradley Cook,BJ Hancock,Anand Kumar,Reeni Soni,Darryl Schantz,Jarrid McKitrick,Xiangguo Qiu,Gary P. Kobinger,Dave Safronetz, Derek Stein,Todd Cutts,James Kenny,Geoff Soule,Robert Kozak,Steven Theriault,James E. Strong

Social Science Research Network（2018）

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Abstract
Introduction: There are currently no licensed treatments for Ebola Virus Disease, making supportive care the only viable option. While there is anecdotal evidence that this is effective, the paucity of experimental data to demonstrate the role of supportive care in EVD has limited its use. We hypothesized that supportive care would enhance survival in a non-human primate (NHP) model of EVD.
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