Synthesis of 2-amino-4 h -pyran-3-carbonitriles its reaction with chloroacetyl chloride

Some ethyl 6-amino-5-cyano-2-methyl-4-aryl-4H-pyran-3-carboxylates were synthesized by reaction of by using three-component reaction included ethyl acetoacetate, malononitrile and appropriate substituted benzaldehydes. The role of different catalysts was examined, including organic and inorganic substances and ionic liquids. Some 2-amino-4H-pyran-3-carbonitriles were converted by reacting with chloroacetyl chloride. The structures of the obtained compounds were confirmed by the modern spectroscopic methods (IR, 1H NMR, 13C NMR).