Influence of laser biomodulation around multifilamentary sutures

Objective: The influence of low level laser (l 670 nm) was evaluated regarding the foreign body reaction and inflammatory response around silk and polyglactin 910 rapid absorbing sutures. Methods: Forty rats were divided into control and irradiated groups and in four subgroups represented by the type of suture material and by the study period - 7 and 14 days. After transfixation of the suture material, the irradiated group was submitted to laser therapy (GaAlAs, 670 nm, 9 mW). Through tissue sections stained with HE, foreign body reaction and inflammatory cell infiltration were analyzed around the wires. Results: Around the silk, foreign body reaction and inflammation were reduced in the groups treated with laser in both periods. Compared to polyglactin 910, laser intensified the presence of multinucleated giant cells. The differences in both sutures and in different groups were not statistically significant. Conclusion: Laser in absorbable sutures increases the foreign body reaction and inflammation in relation to non-absorbable sutures.