Rankl Inhibitor Enhances Bone Modeling after Surgical Fixation for Atypical Femoral Fracture: A Case Report and Review of Management Options

Orthopedic Research Online Journal(2018)

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Abstract
Atypical femoral fracture (AFF) may be associated with prolonged bisphosphonate. Any bisphosphonate after surgical fixation for AFF should not prescribe in this group of patients. Additionally, animal studies have shown that bisphosphonates suppress bone formation by lining cells, that is, bone modeling [1,2]. RANKL-inhibitor is one of the most effective treatment for osteoporosis after surgical intervention for AFF without bone modeling suppression.
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Key words
atypical femoral fracture,surgical fixation
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