ISG56/IFIT1家族研究进展 Research Progress of ISG56/IFIT1 Family

ISG56/IFIT1家族是干扰素刺激基因的成员，其被病毒或干扰素调控，在抗病毒免疫以及干扰素信号通路的调控中发挥了多种生物学功能。本文对ISG56家族基因结构、蛋白特点、调控通路、表达特点和生物学功能等最新研究进展进行总结和归纳。 ISG56/IFIIT1 family are the members of IFN-stimulated genes. They are regulated by virus or IFN, and they perform a variety of biological functions in antiviral immunity and the regulation of interferon signaling pathway. In this paper, the recent progress of ISG56 family, including gene structure, protein characteristics, regulatory pathway, expression characteristics and biological functions was summarized.