Infectious complications of induction treatment for acute myeloid leukaemia using the "7 + 3" protocol without antibiotic prophylaxis - 15 years of experience of one clinical site.

Martin Cernan,Tomas Szotkowski, Jaromir Hubacek,Milan Kolar,Edgar Faber,Karel Indrak,Tomas Papajik

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia（2022）

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摘要

Infectious mortality during induction treatment without routine antibiotic prophylaxis was comparable to the published cohorts with prophylaxis. Regular microbiology surveillance with adequate initial antibiotic treatment can compensate routine antibiotic prophylaxis with slower development of antibiotic resistance.

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关键词

acute myeloid leukaemia, induction therapy, infectious complications, antibiotic prophylaxis, antibiotic resistance, mortality

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