The Effect of Factor-XI (rs3756008) Polymorphism on Recurrent Pregnancy Loss in Iranian Azeri Women

Background Recurrent pregnancy loss (RPL) is a heterogeneous condition consisting of three or more consecutive abortions before the 20 weeks of gestation. Despite extensive research to explain the causative effects of RPL, about 50–60% of RPLs are still idiopathic. Despite the increasing prospective studies with sufficient power related to the association between various thrombophilias and RPL, controversy still remains regarding screening for thrombophilia in women with RPL. The objective of this study was investigate the association between RPL and polymorphism in Factor II G20210A gene in Iranian Azeri women.