Significance of Peripheral Blood Neutrophil to Lymphocyte Ratio in the Prognosis of Breast Cancer

目的：本研究旨在探讨NLR与乳腺癌各分子分型预后的关系。方法：回顾性研究秦皇岛市第一医院2009年1月至2011年1月经过病理学确诊的初治乳腺癌患者263例，通过ROC曲线，兼顾敏感性及特异性确定NLR截点(NLR = 2.08)，分为高NLR组(NLR > 2.08)和低NLR组(NLR 2.08组65.00%，NLR 2.08乳腺癌患者较NLR 2.08). Statistical analysis was performed with the statistical package for the social sciences (SPSS) software package version 19.0. We explore the relationship between NLR and clinical factors on prognosis by calculating 5-year survival rate. Results: 1) In term of age, history of cancer and menopausal status, there was no statistically significant difference. NLR difference between lower and upper groups has statistics significance (P 2.08 group, it was 65.00%; in NLR 2.08 is worse than that in patients with NLR < 2.08. NLR, clinical stages and the molecular subtype are independent factors which influence the prognosis of breast cancer patients.