喘息治療用の高度に選択的で経鼻投与のToll様レセプター7アゴニスト6‐アミノ‐2‐{[(1S)‐1‐メチルブチル]オキシ}‐9‐[5‐(1‐ピペリジニル)ペンチル]‐7,9‐ジヒドロ‐8H‐プリン‐8‐オン(GSK2245035)の発見
Biggadike Keith, Ahmed Mahbub,I Ball Doug,M Coe Diane,Wilk Deidre A. Dalmas,D Edwards Chris,H Gibbon Bob, J Hardy Charlotte,A Hermitage Stephen, O Hessey Joanne, E Hillegas Aimee,C Hughes Stephen,Lazarides Linos,Q Lewell Xiao, Lucas Amanda,N Mallett David,A Price Mark, M Priest Fiona,J Quint Diana,Shah Poonam, Sitaram Anesh,A Smith Stephen,Stocker Richard,A Trivedi Naimisha,C Tsitoura Daphne, Weller Victoria Journal of Medicinal Chemistry（2016）
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