Эффективность трансплантации гемопоэтических стволовых клеток с различными по интенсивности режимами кондиционирования у детей и подростков с миелодиспластическим синдромом

Russian Journal of Children Hematology and Oncology(2017)

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摘要
Treatment results of hematopoietic stem cells transplantation (HSCT) with myeloablative (MAC) and reduced intensity (RIC) conditioning regimen in children and adolescents with myelodysplastic syndrome (MDS). Fifty seven patients aged 1to18 years who received allo-HSCT from 1996 to 2016 (30 patients with MAC and 29 patients with RIC) are included in the study. Analysis of overall and event-free survival in both groups showed comparable efficacy. The use of RIC as alternative conditioning regimen in children and adolescents with MDS.
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hematopoietic stem cell transplantation
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