BNT162b2 mRNA vaccination did not prevent an outbreak of SARS COV-2 variant 501Y.V2 in an elderly nursing home but reduced transmission and disease severity.

Benoit Bailly,Luc Guilpain,Kevin Bouiller,Catherine Chirouze, Melissa N'Debi,Alexandre Soulier,Vanessa Demontant,Jean-Michel Pawlotsky,Christophe Rodriguez,Slim Fourati

Clinical Infectious Diseases（2021）

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摘要

We report an outbreak of SARS-CoV-2 501Y.V2 in a nursing home. All non-vaccinated residents (5/5) versus half of those vaccinated with BNT162b2 (13/26) were infected. Two of 13 vaccinated versus 4 of 5 non-vaccinated residents presented severe disease. BNT162b2 did not prevent the outbreak, but reduced transmission and disease severity.

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