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Simultaneous Diffuse Optical and Bioluminescence Tomography to Improve Source Localization

Alexander Bentley,Xiangkun Xu,Zijian Deng,Jonathan E. Rowe,Ken Kang-Hsin Wang,Hamid Dehghani

DIFFUSE OPTICAL SPECTROSCOPY AND IMAGING VIII（2021）

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Abstract
A novel algorithm to simultaneously recover bioluminescence source location and optical parameters is developed. In-vivo studies show 30% improvement in localization error while also providing local total hemoglobin concentration.
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