Reirradiação em paciente com cancro da mama tratada por linfoma de Hodgkin

The long-term survival of the Hodgkin’s lymphoma patients treated at an early age with chemoradiotherapy is raising awareness for the late effects of this treatment. Radio-induced breast cancer is one of the described risks and occurs almost exclusively after a period of 10 years. Well-established risk factors include the diagnosis in the 10-16 age group, the use of extended-field radiation therapy and an increase in radiation dose. Conservative breast surgery with adjuvant radiotherapy is feasible, but dose-reduction techniques to organs at risk should be considered, given the previous irradiation. We report a clinical case of a secondary breast cancer in a patient who underwent chemoradiotherapy, with mantle field radiation therapy, for supradiaphragmatic Hodgkin’s lymphoma at youth. After multidisciplinary discussion and given the patient’s willingness to preserve the breast, she was treated with conservative breast surgery and adjuvant radiotherapy.