Evaluation of Corneal Stromal Demarcation Line Depth in Epithelium-Off Standard, Epithelium-Off Accelerated and Transepithelial Cross-Linking in Keratectasia

Background: Corneal collagen cross-linking (CXL) has been increased to moderate and halt the development of keratoconus and LASIK ectasia as a viable method. This research is intended to research the corneal current demarcation line (DL) and to compare the depth of the Corneal Strom Demarcation Line utilising anterior segment epithelial, epithelial, accelerated, and transepithelial interconnection (AS-OCT). Methods: Methods: 24 Eyes that match the criteria for inclusion of Cross-Linking patients split evenly into three interventions throughout the last 6 months were included in this research. Topcon 3D spectral domain OCT 2000 was used to measure the demarcation line depth. Outcomes: The DL depth indicated an overall significant difference in the conventional epi-off group (340 microns) across analysed groups, which is much greater than the accelerated epi-off (267 microns) and the accelerated epi-on (190 microns). In the accelerated epi-off it was also much greater than the accelerated epi-on. Conclusion: stromal demarcation line revealed a larger depth in the standard epidemic than rapid epidemic, which depth is higher than that of transepithelial cross-linking, meaning that standard epidema, accelerated epidemic and transepitude techniques are used to determine a larger depth of treatment.