CT-VISIBLE MICROSPHERES ENABLE IN VIVO TRACKING OF BIOMATERIAL DISTRIBUTION AFTER ULTRASOUND-GUIDED INTRAMYOCARDIAL INJECTION

Efficacy of cell therapies are often diminished by low cell retention. A method to visualise the location of grafted cells and biomaterials after delivery could be used to optimise therapies by verifying injection success, retention of the therapeutic and distribution of the product. To address these challenges an injectable cell-substrate consisting of highly porous microspheres containing the computed tomography (CT) contrast agent barium sulphate (BaSO4) was developed.Porous microspheres ( Conflict of Interest None