Сердечно-сосудистый статус и динамика эхокардиографических показателей лиц, перенесших COVID-19 пневмонию, через три месяца после выписки из стационара

Д. В. Криночкин, Е. И. Ярославская,Н. Е. Широков, Е. П. Гультяева, И. Р. Криночкина, И. О. Коровина, А. В. Мамарина,Н. А. Осокина, Н. Н. Мельников, Т. А. Трифанова, Е. А. Горбатенко, Т. И. Петелина

Russian Journal of Cardiology(2021)

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Abstract
Coronavirus disease 2019 (COVID-19) affects the function of all organs and systems. Today, studying the effect of COVID-19 on cardiovascular system, including on echocardiographic characteristics, is relevant. Aim . To study the prevalence of symptoms, cardiovascular disease and changes in echocardiographic data in persons after documented COVID-19 pneumonia 3 months after discharge from the hospital. Material and methods . The study included 106 patients after documented COVID-19 pneumonia. The patients underwent a comprehensive examination during hospitalization and 3 months±2 weeks after discharge from the hospital. The mean age of participants was 47±16 years (19-84 years); 49% of subjects were women. Results . Three months after hospital discharge, the symptoms persisted in 86% of examined patients. There were significant echocardiographic changes as follows: a decrease in LV end-diastolic, end-systolic and stroke volume (113,8±26,8 ml vs 93,5±29,4 ml; 37,7±13,0 ml vs 31,3±14,2 ml; 77,2±17,8 ml vs 62,2±18,7 ml, respectively, p <0,001) and maximum width (36,1±4,6 mm vs 34,5±6,5 mm, p=0,023) decreased, while the right atrial maximum length increased (46,7±6,8 mm vs 48,6±7,1 mm, p=0,021). Conclusion . In survivors of COVID-19 pneumonia three months after hospital discharge, complaints persisted in 86% of cases. Cardiovascular diseases were detected in 52% of participants, including hypertension in 48,1% and coronary artery disease in 15,1%. Compared with in-hospital data, the echocardiographic characteristics improved, which was expressed mainly in a decrease in right heart load.
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Key words
pneumonia,cardiovascular status,echocardiographic changes,survivors
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