The Relations of Brugada ECG Pattern and Fraqmented QRS in Patient with Schizophrenia

Objective: Schizophrenia is a psychiatric disease with high risk of fatal rhythm disorders and sudden cardiac death. A previous study reported that Brugada syndrome was highly prevelant in patients with schizophrenia. In this study we aimed to investigate the prevelance of Brugada syndrome and fraqmanted QRS in patients with schizophrenia. Methods: Two hundred and fifty patients with schizophrenia who were followed up in the psychiatry clinic, and 400 age- and sex-matched non schizophrenia controls were included. Standart ECGs and high intercostal ECGs with V1 and V2 derivation above two intercostal intervals were taken. Results: In schizophrenia patients, Type 1 Brugada syndrome was not observed, Type 2 Brugada was identified in one subject and Type 3 Brugada was observed in two patients. In the control group, Type 2 Brugada pattern was identified in one subject and again one control had Type 3 Brugada pattern(p=0.320). The fragmented QRS (fQRS) incidence, QRS duration and corrected QT were observed to be higher in the schizophrenia group compared to the control group (p=0.001, p=0.003, p