Abstract 14184: Identification of Small Molecules That Ameliorate Morphological Abnormalities of Hypertrophic Cardiomyopathy in Human IPS Cell-Derived Cardiomyocytes

Kohei Deguchi,Shigeru Kondo, Ayaka Sakoda,Kenichi Imahashi,Kenji Miki,Tomoyuki Nishimoto,Tsukasa Sugo,Yoshinori Yoshida

Circulation（2019）

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摘要

Introduction: Hypertrophic cardiomyopathy (HCM) is mainly associated with mutations in sarcomere protein genes, such as MYH7. However, the molecular mechanisms of the HCM phenotype, such as cardiac...

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hypertrophic cardiomyopathy,cell-derived

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