Synthesis of Isoquinolines via Rh(III)‐Catalyzed C−H Annulation of Primary Benzylamines with α‐Cl Ketones

Ruirui Zhai,Dan Xu,Lili Bai,Shuojin Wang,Dulin Kong,Xun Chen

Asian Journal of Organic Chemistry（2022）

Cited 2|Views2

No score

Abstract

An efficient Rh(III)‐catalyzed C−H activation and annulation cascade of primary benzylamines with readily accessible α‐Cl ketones was developed. This transformation provides an easy and robust approach to diverse isoquinolines under air with broad functional group tolerance.

Translated text

Key words

Annulation Cascade,Benzylamines,C−H activation,Rhodium,α-Cl Ketones

AI Read Science

Must-Reading Tree

Example

Generate MRT to find the research sequence of this paper

Chat Paper

Summary is being generated by the instructions you defined