Synthesis of Isoquinolines via Rh(III)‐Catalyzed C−H Annulation of Primary Benzylamines with α‐Cl Ketones

Asian Journal of Organic Chemistry(2022)

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Abstract
An efficient Rh(III)‐catalyzed C−H activation and annulation cascade of primary benzylamines with readily accessible α‐Cl ketones was developed. This transformation provides an easy and robust approach to diverse isoquinolines under air with broad functional group tolerance.
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Key words
Annulation Cascade,Benzylamines,C−H activation,Rhodium,α-Cl Ketones
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